Dual-Mode Redox Sensor for Early Sepsis Detection CSR Proposal

Development of a 'Dual mode' Chemical Sensor for Monitoring the Redox Status of Human Blood Plasma or Cells with Potential Use in the Early Detection of SEPSIS

Objective

• Develop a dual-mode chemical sensor for monitoring blood plasma or cell redox status, enabling early SEPSIS detection by tracking variations in ROS and H2S levels.

Description

• Develop chemical probes sensitive to ROS and H2S., Validate analytical methods for blood plasma., Analyze clinical samples from SEPSIS-prone patients and kidney disease cases., Develop predictive models for early SEPSIS detection.

Impact

• This project aims to transform SEPSIS diagnosis by providing an early detection tool. It can significantly reduce SEPSIS-related mortality rates, especially in immuno-compromised patients, and enhance healthcare outcomes. Furthermore, the sensor's versatility may have broader applications in managing various redox-related chronic diseases, benefitting public health and healthcare systems.