Developing low-cost natural product-based drugs for Parkinson's disease
Principal Investigator
Prof. Amal Kanti Bera
Objective
- Develop affordable, plant-based natural products for the treatment of Parkinson's Disease (PD), reducing the financial burden on patients, particularly those in low-income groups.
Description
- Problem: PD is a costly, neurodegenerative disorder linked to environmental factors like pesticides, affecting millions globally., Solution: Screen a library of polyphenolic compounds for neuroprotective effects using cell line and zebrafish models, and test promising formulations on PD patients., Methodology: Conduct screenings, toxicity assessments, and formulation tests in stages, starting from cell lines to human subjects., Beneficiaries: Low-income individuals, especially those exposed to environmental toxins.
Impact
- This project aims to provide affordable PD treatment options, addressing the financial burden on patients. It can benefit those from economically disadvantaged backgrounds and contribute to improved PD management.